Mouth cancer
In the UK, around 4000 cases of mouth cancer are diagnosed annually. This type of head and neck cancer is more common in men than women.
Reviewed by Mr Alastair Fry, Consultant Oral & Maxillofacial Surgeon
At a glance
What is it?
Mouth cancer is a type of head and neck cancer which develops within the squamous cells that line the mouth, tongue and lips.
How is it diagnosed?
Diagnostic tests for mouth cancer include flexible nasoendoscopy, biopsies and imaging procedures.
How is it treated?
The two main treatments for mouth cancer are surgery or radiotherapy.
What is mouth cancer?
Mouth cancer, also known as oral cancer, can occur anywhere within the mouth, but is most commonly found in the tongue, the lips, and the floor of the mouth. Mouth cancer occurs when abnormal cells begin to grow out of control and develop into tumours.
Mouth cancer is one of the most common types of head and neck cancer. It is more common in men, with 1 in 75 men being diagnosed in their lifetime compared to 1 in 150 women.
Cromwell Hospital is the leading private hospital in London for the diagnosis and treatment of mouth cancer.
Many people who develop mouth cancer have no risk factors. However, you may be at additional risk of developing mouth cancer in the following instances:
- You have previously had head and neck cancer
- You take immuno-suppressive medication
- You have prolonged sun exposure (lip cancer)
- You are infected with human papillomavirus (HPV oral cancer)
- You have oral lichen planus
- You have been exposed to radiation
- You chew betel quid (a type of herbal stimulant).
Early warning signs of mouth cancer include abnormal patches of skin within the mouth:
- Erythroplakia – A red, raised patch of skin that bleeds if scraped. About 70% of erythroplakias are cancerous or pre-cancerous.
- Leukoplakia – A white spot or patch of skin. About 25% of leukoplakias are cancerous or pre-cancerous.
- Erythroleukoplakia – A patch of skin with both white and red areas.
Other symptoms include:
- Oral ulcers or sores that are painful and do not heal
- A lump in the neck, face, jaw, cheek, tongue or gums
- Unexplained loose teeth
- Difficulty chewing, swallowing or moving the tongue or jaw
- Dentures that cause discomfort or do not fit well
- Bad breath
- Weight loss.
If you are diagnosed with mouth cancer, your condition will be graded based on its severity. Assigning a stage to your condition helps your consultant determine the best course of treatment for you.
There are three staging points for mouth cancer:
- T – The size of the primary tumour and how much it has invaded surrounding tissues
- N – Whether the cancer has spread to the lymph nodes
- M – Whether the cancer has spread elsewhere in the body (usually the lungs).
The size of the tumour (staging point T) is graded from numbers one through to five. The higher the number, the larger and more invasive the tumour is considered to be.
Our multidisciplinary approach
At Cromwell Hospital, our head and neck surgeons have extensive experience in treating mouth cancer patients, as well as delivering reconstructive surgery. We provide the best chance for successful mouth cancer treatment with the least effects on your health.
With our multidisciplinary approach to patient care, you can be rest assured that you are receiving the best, most informed treatment plan possible, with input from a wide range of medical experts. You will also receive extensive support before, during, and after treatment, through cancer counselling sessions, speech and language therapy, dietary advice, and more.
In 2022, we established our first-of-its-kind Head and Neck Survivorship Clinic to provide support services to individuals with head and neck cancer. Our multidisciplinary service – which includes surgery, oral medicine, restorative dentistry, speech and language therapy, dietary advice, and physiotherapy – helps patients navigate their diagnosis and any obstacles they face, as well as monitoring patients post-treatment and providing support with symptom management.
Diagnostic tests for mouth cancer
As well as a physical examination of your mouth and lymph nodes, you may also need to undergo some of the following procedures for a diagnosis to be made:
MRI scan
A magnetic resonance imaging (MRI) scan uses magnetic fields and radio waves to produce images from inside the body.
PET-CT scan
A PET-CT scan uses radioactive tracers injected into the bloodstream to help assess the biological activity of tumours.
CT scan with contrast
A computer tomography (CT) scan uses X-rays and computer software to create detailed images from inside the body.
Ultrasound
An ultrasound scan uses high frequency soundwaves to create detailed images of internal organs.
Biopsy
A biopsy involves taking a small piece of tissue for further examination. There are two types used for mouth cancer diagnosis: incisional and fine needle aspiration (FNA).
X-ray
A dental X-ray scan is often used to identify any problems with the teeth or jaw prior to beginning mouth cancer treatment.
Flexible nasendoscopy
Flexible nasendoscopy (FNE) uses a small camera to examine the nasal and sinus passages for signs of lesions.
Mouth cancer treatment
At our Integrated Cancer Campus, we provide two types of treatment for mouth cancer: surgery and radiotherapy. Both types of treatment aim to eliminate the tumour(s).
Surgery involves removing both the tumour and a small portion of surrounding tissue – this surrounding tissue must be removed or the tumour will re-grow. Sometimes, this means removing part of structures like the jaw, which can require reconstructive surgery to restore.
Glossectomy
A glossectomy is a type of surgery that involves the partial or full removal of the tongue.
Mandibulectomy
A mandibulectomy refers to the surgical removal of part of the lower jaw (mandible).
Maxillectomy
A maxillectomy is a surgical procedure used to remove part or all of the upper jaw (maxilla).
Buccal mucosa surgery
This type of surgery is used to remove the diseased portion of the cheek lining (buccal mucosa).
Temporary tracheostomy
A tracheostomy involves the placement of a tube that acts as a temporary airway for the patient.
Free flap surgery
Free flap surgery aims to restore the function and appearance of the head and neck area following cancer surgery.
Radiotherapy
Radiotherapy uses high-energy beams (X-rays) or radiation to destroy the DNA inside cancer cells.
Clinical interests: Mouth cancer; head and neck cancer; oral precancers and white patches; jaw surgery and reconstruction; salivary gland disease (stones and tumours); wisdom teeth (third molars); dentoalveolar (oral surgery); implants and trauma.
Languages spoken: English
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